Product Details
Acyclovir injection
250MG/500MG
Product Description :
ACYCLOVIR INJECTION 250 mg / 500 mg
Sterile Powder for Solution for Intravenous Administration
1. COMPOSITION
Each vial contains:
• Acyclovir Sodium equivalent to Acyclovir 250 mg / 500 mg.
• Excipients: As applicable.
2. PHARMACEUTICAL FORM
Sterile, white to off-white powder for solution for intravenous administration.
3. THERAPEUTIC CLASS
Antiviral Agent – Nucleoside Analogue.
4. INDICATIONS
Acyclovir Injection is indicated for the treatment of serious infections caused by Herpes simplex virus (HSV) and Varicella-zoster virus (VZV), including:
• Severe or disseminated Herpes simplex infections.
• Herpes simplex encephalitis.
• Severe Varicella-zoster infections.
• Herpes zoster in immunocompromised patients.
• Other serious HSV/VZV infections where intravenous antiviral therapy is appropriate.
Treatment should be guided by the clinical condition and applicable antiviral guidelines.
5. CONTRAINDICATIONS
• Hypersensitivity to acyclovir, valacyclovir, or any component of the formulation.
• Use should be carefully evaluated in patients with significant renal impairment.
6. DRUG INTERACTIONS
• Other nephrotoxic medicines may increase the risk of renal toxicity.
• Probenecid may affect acyclovir elimination.
• Mycophenolate mofetil may increase acyclovir exposure.
• Other medicines affecting renal function should be used with caution.
The treating physician should review all concomitant medications before administration.
7. ADMINISTRATION
For intravenous administration only. Reconstitute and dilute with a compatible diluent under aseptic conditions and administer by slow intravenous infusion according to the approved product information and institutional protocol. Adequate hydration and appropriate renal function monitoring should be considered during therapy.
8. STORAGE
Store according to the storage conditions stated on the approved product label. Protect from excessive heat, moisture and light. After reconstitution/dilution, use within the period specified in the approved product information. Do not use if the reconstituted solution shows visible particles, precipitation or unexpected discoloration.